Peyote & Mescaline — Deep Dive

The cactus medicines. Full pharmacology, outcomes data, and readiness framework.

The Pharmacology

Mescaline is a phenethylamine that acts primarily as a 5-HT2A receptor agonist — the same mechanism as psilocybin and LSD. Duration: 8-12 hours. Onset: 1-2 hours. Threshold dose: 100-150mg mescaline HCl equivalent.